Login ㆍ Sign up
Updated: 2018.9.27 05:17
 
HOME > NEWS > News > Highlights
     
NK Cells and Pregnancy
[ Issue 161 Page 2 ] Wednesday, April 11, 2018, 13:24:16 Hongseok Lee Junior Staff Reporter leehong@kaist.ac.kr

During pregnancy, the fetus is presented with a safe environment within the mother’s womb and is supplied with nutrition essential for its growth. This means that what exists in the womb during pregnancy contributes to regulated fetus growth. Yet, little was known about the function of natural killer (NK) cells within the uterine microenvironment until a recent discovery by the Columbia University Medical Center (CUMC).

Researchers in CUMC discovered that uterine NK cells work as an immune system by eliminating intracellular pathogens. They also demonstrated how NK cells facilitates fetal growth by promoting the production of pleiotrophin, osteoglycin, and osteopontin, all of which are growth-promoting factors, in mice. Fetal growth involves processes such as cell expansion, cellular specialization, and generation of specific organs in a chronological order. Hence, regulation of the growth factors is crucial. When the NK cells were removed from a mother’s fetus, it led to defective fetal development at best and miscarriage at worst. The discovery is significant as it can lead to providing a safer fetal environment during pregnancy.

Hongseok Lee Junior Staff Reporter Archives  
Twitter Facebook Google
ⓒ KAIST Herald 2011 (http://herald.kaist.ac.kr)
All materials on this site are protected under the Korean Copyright Law and may not be reproduced, distributed, transmitted, displayed, published without the prior consent of KAIST Herald.

     
Total comments(0)  
      Enter the code!   
 
   * Readers can write comments up to 200 words (Current 0 byte/Max 400byte)
About Us | Privacy Policy | Rights and Permissions | Article Submission | RSS | Contact Us
The KAIST Herald, Undergraduate Library, KAIST, Daejeon, Republic of Korea
Publisher: Sung-Chul Shin | Managing Editor: Jeounghoon Kim | Editor: Sejoon Huh
Copyright 2011-2018 The KAIST Herald | All rights reserved | Mail to: kaistherald@gmail.com