With development in medicine, antibiotic-resistant super bacteria have become one of humanity’s worst enemies. However, a team led by Dr. Serge Mostowy from Imperial College London and Professor Liz Sockett from the University of Nottingham may have found a solution for these foes. Using the predatory bacterium Bdellovibrio bacteriovorus, the team tested its strength against drug-resistant Shigella infections, which are the common cause of “traveler’s diarrhea” and are responsible for over 1 million deaths each year. When injecting lethal doses of this Gram-negative infection in zebrafish larvae, researchers observed those with Bdellovibrio had decreases in their Shigella populations while those without the predator bacterium were unable to control the number of Shigella. Dr. Mostowy said the study shows the amazing, natural synergy Bdellovibrio has with the immune system and that “it’s an important milestone in research into the use of a living antibiotic”. Its effectiveness against Gramnegative bacteria such as E. Coli and Salmonella further emphasizes the role of Bdellovibrio in the future of battling super bacteria. The team’s results have been published in Current Biology.

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